Regadenoson is a selective adenosine 2a (A2a) receptor agonist navy blue lantern that is used in cardiac stress testing to evaluate for ischemic heart disease and has largely replaced adenosine in the modern era.Since adenosine receptors are involved in synaptic transmission between neurons throughout the central nervous system (CNS) including the
Lack of significant advancements in early detection and treatment of heart failure have precipitated the need for discovery navy blue lantern of novel biomarkers and therapeutic targets.Over the past decade, circulating sphingolipids have elicited promising results as biomarkers that premonish adverse cardiac events.Additionally, compelling evidenc
The Dolese Limestone Quarry near Richards Spur, Oklahoma includes an elaborate system of caves which have been infilled with early Permian fossil rich sediments.In operation for more than a century, the quarry yielded vast numbers of disarticulated skeletal elements of the most diverse assemblage of fully terrestrial tetrapods from the Paleozoic.Ex
Numerical Relativity is a multidisciplinary field including relativity, magneto-hydrodynamics, astrophysics and computational methods, among others, with camif commode the aim of solving numerically highly-dynamical, strong-gravity scenarios where no other approximations are available.Here we describe some of the foundations of the field, starting
The goal of this work is to compile and discuss molecules of marine origin reported in the scientific literature with anti-parasitic activity against Trichomonas, Giardia, and Entamoeba, parasites responsible for diseases that are major global health problems, and Microsporidial parasites as an emerging problem.The presented data correspond to meta